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Papain-Like Proteases as Coronaviral Drug Targets: Current Inhibitors, Opportunities, and Limitations

Papain-like proteases (PLpro) of coronaviruses (CoVs) support viral reproduction and suppress the immune response of the host, which makes CoV PLpro perspective pharmaceutical targets. Their inhibition could both prevent viral replication and boost the immune system of the host, leading to the speed...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Petushkova, Anastasiia I., Zamyatnin, Andrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601131/
https://ncbi.nlm.nih.gov/pubmed/32998368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13100277
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