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Papain-Like Proteases as Coronaviral Drug Targets: Current Inhibitors, Opportunities, and Limitations

Papain-like proteases (PLpro) of coronaviruses (CoVs) support viral reproduction and suppress the immune response of the host, which makes CoV PLpro perspective pharmaceutical targets. Their inhibition could both prevent viral replication and boost the immune system of the host, leading to the speed...

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Autores principales: Anastasiia I. Petushkova, Andrey A. Zamyatnin
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2020-09-01
Colección:Pharmaceuticals
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Acceso en línea:https://www.mdpi.com/1424-8247/13/10/277
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