IL-12 and IL-23—Close Relatives with Structural Homologies but Distinct Immunological Functions

Cytokines of the IL-12 family show structural similarities but have distinct functions in the immune system. Prominent members of this cytokine family are the pro-inflammatory cytokines IL-12 and IL-23. These two cytokines share cytokine subunits and receptor chains but have different functions in a...

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Bibliographic Details
Published in:Cells
Main Authors: Floss, Doreen M., Moll, Jens M., Scheller, Jürgen
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7600943/
https://ncbi.nlm.nih.gov/pubmed/32998371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102184
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