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Humanization of Drosophila Gαo to Model GNAO1 Paediatric Encephalopathies
Several hundred genes have been identified to contribute to epilepsy—the disease affecting 65 million people worldwide. One of these genes is GNAO1 encoding Gαo, the major neuronal α-subunit of heterotrimeric G proteins. An avalanche of dominant de novo mutations in GNAO1 have been recently describe...
Kaydedildi:
| Yayımlandı: | Biomedicines |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
MDPI
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7599900/ https://ncbi.nlm.nih.gov/pubmed/33036271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8100395 |
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