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Humanization of Drosophila Gαo to Model GNAO1 Paediatric Encephalopathies
Several hundred genes have been identified to contribute to epilepsy—the disease affecting 65 million people worldwide. One of these genes is GNAO1 encoding Gαo, the major neuronal α-subunit of heterotrimeric G proteins. An avalanche of dominant de novo mutations in GNAO1 have been recently describe...
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| Publicado no: | Biomedicines |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7599900/ https://ncbi.nlm.nih.gov/pubmed/33036271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8100395 |
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