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Water Thermodynamics of Peptide Toxin Binding Sites on Ion Channels

Peptide toxins isolated from venomous creatures, long prized as research tools due to their innate potency for ion channels, are emerging as drugs as well. However, it remains challenging to understand why peptide toxins bind with high potency to ion channels, to identify residues that are key for a...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Shah, Binita, Sindhikara, Dan, Borrelli, Ken, Leffler, Abba E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599640/
https://ncbi.nlm.nih.gov/pubmed/33053750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12100652
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