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Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells

The logical AND gate gene circuit based on the CRISPR-Cas9 system can distinguish bladder cancer cells from normal bladder epithelial cells. However, the layered artificial gene circuits have the problems of high complexity, difficulty in accurately predicting the behavior, and excessive redundancy,...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Liu, Yuchen, Huang, Weiren, Cai, Zhiming
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599332/
https://ncbi.nlm.nih.gov/pubmed/33127914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19314-7
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