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AB111. Synthesizing an AND gate genetic circuit for identification of bladder cancer cells based on CRISPR-Cas9

BACKGROUND: Because of the lack of an ideal promoter that selectively identifies cancer cells and robustly drives therapeutic gene expression, the conventional strategy for cancer gene therapy offers limited control of specificity and efficacy. A possible way to overcome these limitations is to cons...

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Detalles Bibliográficos
Publicado en:Transl Androl Urol
Main Authors: Liu, Yuchen, Huang, Weiren, Cai, Zhiming
Formato: Artigo
Idioma:Inglês
Publicado: AME Publishing Company 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4708460/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2223-4683.2014.s111
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