Single-cell analysis of AIMP2 splice variants informs on drug sensitivity and prognosis in hematologic cancer

Aminoacyl-tRNA synthetase-interacting multifunctional protein 2 (AIMP2) is a non-enzymatic component required for the multi-tRNA synthetase complex. While exon 2 skipping alternatively spliced variant of AIMP2 (AIMP2-DX2) compromises AIMP2 activity and is associated with carcinogenesis, its clinical...

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Publicado en:Commun Biol
Main Authors: Ku, Jayoung, Kim, Ryul, Kim, Dongchan, Kim, Daeyoon, Song, Seulki, Lee, Keonyong, Lee, Namseok, Kim, MinA, Yoon, Sung-Soo, Kwon, Nam Hoon, Kim, Sunghoon, Kim, Yoosik, Koh, Youngil
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599330/
https://ncbi.nlm.nih.gov/pubmed/33128014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01353-x
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