Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation

BACKGROUND: Ventilator-associated pneumonia is the most common intensive care unit (ICU)-acquired infection, yet accurate diagnosis remains difficult, leading to overuse of antibiotics. Low concentrations of IL-1β and IL-8 in bronchoalveolar lavage fluid have been validated as effective markers for...

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Bibliografiset tiedot
Julkaisussa:Lancet Respir Med
Päätekijät: Hellyer, Thomas P, McAuley, Daniel F, Walsh, Timothy S, Anderson, Niall, Conway Morris, Andrew, Singh, Suveer, Dark, Paul, Roy, Alistair I, Perkins, Gavin D, McMullan, Ronan, Emerson, Lydia M, Blackwood, Bronagh, Wright, Stephen E, Kefala, Kallirroi, O'Kane, Cecilia M, Baudouin, Simon V, Paterson, Ross L, Rostron, Anthony J, Agus, Ashley, Bannard-Smith, Jonathan, Robin, Nicole M, Welters, Ingeborg D, Bassford, Christopher, Yates, Bryan, Spencer, Craig, Laha, Shondipon K, Hulme, Jonathan, Bonner, Stephen, Linnett, Vanessa, Sonksen, Julian, Van Den Broeck, Tina, Boschman, Gert, Keenan, DW James, Scott, Jonathan, Allen, A Joy, Phair, Glenn, Parker, Jennie, Bowett, Susan A, Simpson, A John
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2020
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599318/
https://ncbi.nlm.nih.gov/pubmed/31810865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2213-2600(19)30367-4
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