Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial

BACKGROUND: Ventilator-acquired pneumonia (VAP) is a common reason for antimicrobial therapy in the intensive care unit (ICU). Biomarker-based diagnostics could improve antimicrobial stewardship through rapid exclusion of VAP. Bronchoalveloar lavage (BAL) fluid biomarkers have previously been shown...

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Dettagli Bibliografici
Pubblicato in:Trials
Autori principali: Hellyer, Thomas P., Anderson, Niall H., Parker, Jennie, Dark, Paul, Van Den Broeck, Tina, Singh, Suveer, McMullan, Ronan, Agus, Ashley M., Emerson, Lydia M., Blackwood, Bronagh, Gossain, Savita, Walsh, Tim S., Perkins, Gavin D., Conway Morris, Andrew, McAuley, Daniel F., Simpson, A. John
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Study Protocol
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947254/
https://ncbi.nlm.nih.gov/pubmed/27422026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-016-1442-x
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