Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial

BACKGROUND: Ventilator-acquired pneumonia (VAP) is a common reason for antimicrobial therapy in the intensive care unit (ICU). Biomarker-based diagnostics could improve antimicrobial stewardship through rapid exclusion of VAP. Bronchoalveloar lavage (BAL) fluid biomarkers have previously been shown...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Hellyer, Thomas P., Anderson, Niall H., Parker, Jennie, Dark, Paul, Van Den Broeck, Tina, Singh, Suveer, McMullan, Ronan, Agus, Ashley M., Emerson, Lydia M., Blackwood, Bronagh, Gossain, Savita, Walsh, Tim S., Perkins, Gavin D., Conway Morris, Andrew, McAuley, Daniel F., Simpson, A. John
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947254/
https://ncbi.nlm.nih.gov/pubmed/27422026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-016-1442-x
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