Functionalization of alginate with extracellular matrix peptides enhances viability and function of encapsulated porcine islets

Translation of transplanted alginate-encapsulated pancreatic islets to treat type 1 diabetes has been hindered by inconsistent long-term efficacy. This loss of graft function can be partially attributed to islet dysfunction associated with the destruction of extracellular matrix (ECM) interactions d...

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Publicat a:Adv Healthc Mater
Autors principals: Medina, Juan D., Alexander, Michael, Hunckler, Michael D., Fernández-Yagüe, Marc A., Coronel, María M., Smink, Alexandra M., Lakey, Jonathan R., de Vos, Paul, García, Andrés J.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598935/
https://ncbi.nlm.nih.gov/pubmed/32255552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.202000102
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