Therapeutic Strategies for Modulating the Extracellular Matrix to Improve Pancreatic Islet Function and Survival After Transplantation

PURPOSES OF REVIEW: Extracellular matrix (ECM) components modulate the interaction between pancreatic islet cells. During the islet isolation prior to transplantation as treatment for type 1 diabetes, the ECM is disrupted impacting functional graft survival. Recently, strategies for restoring ECM ha...

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Bibliographic Details
Published in:Curr Diab Rep
Main Authors: Smink, Alexandra M., de Vos, Paul
Format: Artigo
Language:Inglês
Published: Springer US 2018
Subjects:
Immunology, Transplantation, and Regenerative Medicine (L Piemonti and V Sordi, Section Editors)
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960477/
https://ncbi.nlm.nih.gov/pubmed/29779190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11892-018-1014-4
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