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Therapeutic Strategies for Modulating the Extracellular Matrix to Improve Pancreatic Islet Function and Survival After Transplantation

PURPOSES OF REVIEW: Extracellular matrix (ECM) components modulate the interaction between pancreatic islet cells. During the islet isolation prior to transplantation as treatment for type 1 diabetes, the ECM is disrupted impacting functional graft survival. Recently, strategies for restoring ECM ha...

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Detalhes bibliográficos
Publicado no:Curr Diab Rep
Main Authors: Smink, Alexandra M., de Vos, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960477/
https://ncbi.nlm.nih.gov/pubmed/29779190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11892-018-1014-4
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