Complement activation and endothelial perturbation parallel COVID-19 severity and activity

BACKGROUND: Animal models and few clinical reports suggest the involvement of the complement system in the onset of severe manifestations of coronavirus disease-2019 (COVID-19). However, complement contribution to endotheliopathy and hypercoagulability has not been elucidated yet. OBJECTIVE: To eval...

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Publicado en:J Autoimmun
Main Authors: Cugno, Massimo, Meroni, Pier Luigi, Gualtierotti, Roberta, Griffini, Samantha, Grovetti, Elena, Torri, Adriana, Lonati, Paola, Grossi, Claudia, Borghi, Maria Orietta, Novembrino, Cristina, Boscolo, Massimo, Uceda Renteria, Sara Colonia, Valenti, Luca, Lamorte, Giuseppe, Manunta, Maria, Prati, Daniele, Pesenti, Antonio, Blasi, Francesco, Costantino, Giorgio, Gori, Andrea, Bandera, Alessandra, Tedesco, Francesco, Peyvandi, Flora
Formato: Artigo
Idioma:Inglês
Publicado: Published by Elsevier Ltd. 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598768/
https://ncbi.nlm.nih.gov/pubmed/33139116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2020.102560
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