Chromosome 3 cluster rs11385942 variant links complement activation with severe COVID-19

BACKGROUND: Genetic variation at a multigene cluster at chromosome 3p21.31 and the ABO blood group have been associated with the risk of developing severe COVID-19, but the mechanism remains unclear. Complement activation has been associated with COVID-19 severity. OBJECTIVE: The aim of this study w...

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Detalhes bibliográficos
Publicado no:J Autoimmun
Main Authors: Valenti, Luca, Griffini, Samantha, Lamorte, Giuseppe, Grovetti, Elena, Uceda Renteria, Sara Colonia, Malvestiti, Francesco, Scudeller, Luigia, Bandera, Alessandra, Peyvandi, Flora, Prati, Daniele, Meroni, Pierluigi, Cugno, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796659/
https://ncbi.nlm.nih.gov/pubmed/33453462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2021.102595
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