Bta-miR-34b inhibits proliferation and promotes apoptosis via the MEK/ERK pathway by targeting MAP2K1 in bovine primary Sertoli cells

Immature Sertoli cell (SC) proliferation determines the final number of mature SCs and further regulates spermatogenesis. Accumulating evidence demonstrated that microRNAs (miRNAs) play an important role in SC proliferation, differentiation, and apoptosis. However, the effect and molecular mechanism...

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Dades bibliogràfiques
Publicat a:J Anim Sci
Autors principals: Zhang, Linlin, Ma, Tiantian, Tao, Qibing, Tan, Wushuang, Chen, Huatao, Liu, Wei, Lin, Pengfei, Zhou, Dong, Wang, Aihua, Jin, Yaping, Tang, Keqiong
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Reproduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598574/
https://ncbi.nlm.nih.gov/pubmed/32954430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jas/skaa313
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