Bta-miR-34b inhibits proliferation and promotes apoptosis via the MEK/ERK pathway by targeting MAP2K1 in bovine primary Sertoli cells

Immature Sertoli cell (SC) proliferation determines the final number of mature SCs and further regulates spermatogenesis. Accumulating evidence demonstrated that microRNAs (miRNAs) play an important role in SC proliferation, differentiation, and apoptosis. However, the effect and molecular mechanism...

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Detalhes bibliográficos
Publicado no:J Anim Sci
Main Authors: Zhang, Linlin, Ma, Tiantian, Tao, Qibing, Tan, Wushuang, Chen, Huatao, Liu, Wei, Lin, Pengfei, Zhou, Dong, Wang, Aihua, Jin, Yaping, Tang, Keqiong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Reproduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598574/
https://ncbi.nlm.nih.gov/pubmed/32954430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jas/skaa313
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