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Chitosan Hydrogel Doped with PEG-PLA Nanoparticles for the Local Delivery of miRNA-146a to Treat Allergic Rhinitis

To prepare a binary formulation delivering miRNA-146 and evaluate a nucleic acid nasal delivery system by investigating its pharmacodynamic effects in allergic rhinitis. The gel/NPs/miR-146a thermosensitive in situ chitosan hydrogel carrying a nucleic acid was prepared and evaluated for its characte...

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Bibliografiske detaljer
Udgivet i:Pharmaceutics
Main Authors: Su, Yu, Sun, Bixi, Gao, Xiaoshu, Liu, Shuwen, Hao, Rubin, Han, Bing
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598290/
https://ncbi.nlm.nih.gov/pubmed/32977497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12100907
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