ERG orchestrates chromatin interactions to drive prostate cell fate reprogramming

Although cancer is commonly perceived as a disease of dedifferentiation, the hallmark of early-stage prostate cancer is paradoxically the loss of more plastic basal cells and the abnormal proliferation of more differentiated secretory luminal cells. However, the mechanism of prostate cancer prolumin...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Li, Fei, Yuan, Qiuyue, Di, Wei, Xia, Xinyi, Liu, Zhuang, Mao, Ninghui, Li, Lin, Li, Chunfeng, He, Juan, Li, Yunguang, Guo, Wangxin, Zhang, Xiaoyu, Zhu, Yiqin, Aji, Rebiguli, Wang, Shangqian, Tong, Xinyuan, Ji, Hongbin, Chi, Ping, Carver, Brett, Wang, Yong, Chen, Yu, Gao, Dong
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598085/
https://ncbi.nlm.nih.gov/pubmed/32701507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI137967
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