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Antihypoxic oxygenation agents with respiratory hyperoxia to improve cancer immunotherapy

Hypoxia/HIF-1α– and extracellular adenosine/A2 adenosine receptor–mediated immunosuppression protects tissues from collateral damage by antipathogen immune cells. However, this mechanism also protects cancerous tissues by inhibiting antitumor immune cells in hypoxic and extracellular adenosine–rich...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Hatfield, Stephen M., Sitkovsky, Michail V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598059/
https://ncbi.nlm.nih.gov/pubmed/32870821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI137554
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