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Structural Contributions to Autocatalysis and Asymmetric Amplification in the Soai Reaction

Diisopropylzinc alkylation of pyrimidine aldehydes – the Soai reaction, with its astonishing attribute of amplifying asymmetric autocatalysis, occupies a unique position in organic chemistry and stands as an eminent challenge for mechanistic elucidation. A new paradigm of ‘mixed catalyst substrate’...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Athavale, Soumitra V., Simon, Adam, Houk, Kendall N., Denmark, Scott E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7597373/
https://ncbi.nlm.nih.gov/pubmed/33108874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c05994
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