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Demystifying the asymmetry-amplifying, autocatalytic behavior of the Soai reaction through structural, mechanistic, and computational studies

The Soai reaction has profoundly impacted chemists’ perspective of chiral symmetry breaking, absolute asymmetric synthesis and its role in the origin of biological homochirality. Herein, we describe the unprecedented observation of asymmetry amplifying autocatalysis in the alkylation of 5-(trimethyl...

詳細記述

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書誌詳細
出版年:Nat Chem
主要な著者: Athavale, Soumitra V., Simon, Adam, Houk, Kendall N., Denmark, Scott E.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7117993/
https://ncbi.nlm.nih.gov/pubmed/32203445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-020-0421-8
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