Large Animal Models of Huntington’s Disease: What We Have Learned and Where We Need to Go Next

Genetically modified rodent models of Huntington’s disease (HD) have been especially valuable to our understanding of HD pathology and the mechanisms by which the mutant HTT gene alters physiology. However, due to inherent differences in genetics, neuroanatomy, neurocircuitry and neurophysiology, an...

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Dades bibliogràfiques
Publicat a:J Huntingtons Dis
Autors principals: Howland, David, Ellederova, Zdenka, Aronin, Neil, Fernau, Deborah, Gallagher, Jill, Taylor, Amanda, Hennebold, Jon, Weiss, Alison R., Gray-Edwards, Heather, McBride, Jodi
Format: Artigo
Idioma:Inglês
Publicat: IOS Press 2020
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7597371/
https://ncbi.nlm.nih.gov/pubmed/32925082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-200425
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