Serum HBsAg clearance has minimal impact on CD8(+) T cell responses in mouse models of HBV infection

Antibody-mediated clearance of hepatitis B surface antigen (HBsAg) from the circulation of chronically infected patients (i.e., seroconversion) is usually associated with increased HBV-specific T cell responsiveness. However, a causative link between serum HBsAg levels and impairment of intrahepatic...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Fumagalli, Valeria, Di Lucia, Pietro, Venzin, Valentina, Bono, Elisa B., Jordan, Robert, Frey, Christian R., Delaney, William, Chisari, Francis V., Guidotti, Luca G., Iannacone, Matteo
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596822/
https://ncbi.nlm.nih.gov/pubmed/32761167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200298
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