Solely HBsAg intrauterine exposure accelerates HBV clearance by promoting HBs-specific immune response in the mouse pups

Chronic hepatitis B virus (HBV) infection due to perinatal mother-to-infant transmission (MTIT) remains a serious global public health problem. It has been shown that intrauterine exposure to HBV antigens might account for the MTIT-related chronic infection. However, whether hepatitis B surface anti...

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Hlavní autoři: Jing Ning, Jianwen Wang, Huiling Zheng, Siwen Peng, Tianhao Mao, Lu Wang, Guangxin Yu, Jia Liu, Shuang Liu, Ting Zhang, Shigang Ding, Fengmin Lu, Xiangmei Chen
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis Group 2022-12-01
Edice:Emerging Microbes and Infections
Témata:
Hepatitis B virus
hepatitis B surface antigen
vertical transmission
intrauterine exposure
adaptive immunity
HBs-specific CD8+ T cells
On-line přístup:https://www.tandfonline.com/doi/10.1080/22221751.2022.2071172
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