Necroptosis restricts influenza A virus as a stand-alone cell death mechanism

Influenza A virus (IAV) activates ZBP1-initiated RIPK3-dependent parallel pathways of necroptosis and apoptosis in infected cells. Although mice deficient in both pathways fail to control IAV and succumb to lethal respiratory infection, RIPK3-mediated apoptosis by itself can limit IAV, without need...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Shubina, Maria, Tummers, Bart, Boyd, David F., Zhang, Ting, Yin, Chaoran, Gautam, Avishekh, Guo, Xi-zhi J., Rodriguez, Diego A., Kaiser, William J., Vogel, Peter, Green, Douglas R., Thomas, Paul G., Balachandran, Siddharth
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596817/
https://ncbi.nlm.nih.gov/pubmed/32797196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191259
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