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Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts

Biocontainment systems are needed to neutralize genetically modified organisms (GMOs) that pose ecological threats outside of controlled environments. In contrast, benign selection markers complement GMOs with reduced fitness. Benign selection agents serve as alternatives to antibiotics, which are c...

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Vydáno v:Nat Commun
Hlavní autoři: Yoo, Justin I., Seppälä, Susanna, OʼMalley, Michelle A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596524/
https://ncbi.nlm.nih.gov/pubmed/33122649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19271-1
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