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Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts

Biocontainment systems are needed to neutralize genetically modified organisms (GMOs) that pose ecological threats outside of controlled environments. In contrast, benign selection markers complement GMOs with reduced fitness. Benign selection agents serve as alternatives to antibiotics, which are c...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Yoo, Justin I., Seppälä, Susanna, OʼMalley, Michelle A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596524/
https://ncbi.nlm.nih.gov/pubmed/33122649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19271-1
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