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Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts

Biocontainment systems are needed to neutralize genetically modified organisms (GMOs) that pose ecological threats outside of controlled environments. In contrast, benign selection markers complement GMOs with reduced fitness. Benign selection agents serve as alternatives to antibiotics, which are c...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Yoo, Justin I., Seppälä, Susanna, OʼMalley, Michelle A.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596524/
https://ncbi.nlm.nih.gov/pubmed/33122649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19271-1
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