Test-statistic inflation in methylome-wide association studies

Recent years have seen a surge of methylome-wide association studies (MWAS). We observed that many of these studies suffer from test statistic inflation that is most likely caused by commonly used quality control (QC) pipelines not going far enough to remove technical artefacts. To support this clai...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Guintivano, Jerry, Shabalin, Andrey A, Chan, Robin F., Rubinow, David R., Sullivan, Patrick F., Meltzer-Brody, Samantha, Aberg, Karolina a, van den Oord, Edwin J. C. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7595582/
https://ncbi.nlm.nih.gov/pubmed/32425094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2020.1758382
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