A MBD-seq protocol for large-scale methylome-wide studies with (very) low amounts of DNA

We recently showed that, after optimization, our methyl-CpG binding domain sequencing (MBD-seq) application approximates the methylome-wide coverage obtained with whole-genome bisulfite sequencing (WGB-seq), but at a cost that enables adequately powered large-scale association studies. A prior drawb...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Aberg, Karolina A., Chan, Robin F., Shabalin, Andrey A., Zhao, Min, Turecki, Gustavo, Staunstrup, Nicklas Heine, Starnawska, Anna, Mors, Ole, Xie, Lin Y., van den Oord, Edwin JCG
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739096/
https://ncbi.nlm.nih.gov/pubmed/28703682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1335849
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