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G82S RAGE polymorphism influences amyloid-RAGE interactions relevant in Alzheimer’s disease pathology

Receptor for advanced glycation end products (RAGE) has been implicated in the pathophysiology of Alzheimers disease(AD) due to its ability to bind amyloid-beta (Aβ42) and mediate inflammatory response. G82S RAGE polymorphism is associated with AD but the molecular mechanism for this association is...

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Publicat a:PLoS One
Autors principals: C, Rani Cathrine., Lukose, Bincy, Rani, P.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7595441/
https://ncbi.nlm.nih.gov/pubmed/33119615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225487
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