Time to first treatment and P53 dysfunction in chronic lymphocytic leukaemia: results of the O-CLL1 study in early stage patients

Chronic lymphocytic leukaemia (CLL) is characterised by a heterogeneous clinical course. Such heterogeneity is associated with a number of markers, including TP53 gene inactivation. While TP53 gene alterations determine resistance to chemotherapy, it is not clear whether they can influence early dis...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Monti, Paola, Lionetti, Marta, De Luca, Giuseppa, Menichini, Paola, Recchia, Anna Grazia, Matis, Serena, Colombo, Monica, Fabris, Sonia, Speciale, Andrea, Barbieri, Marzia, Gentile, Massimo, Zupo, Simonetta, Dono, Mariella, Ibatici, Adalberto, Neri, Antonino, Ferrarini, Manlio, Fais, Franco, Fronza, Gilberto, Cutrona, Giovanna, Morabito, Fortunato
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7595214/
https://ncbi.nlm.nih.gov/pubmed/33116240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75364-3
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