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Mechanism of aminoacyl-tRNA acetylation by an aminoacyl-tRNA acetyltransferase AtaT from enterohemorrhagic E. coli

Toxin-antitoxin systems in bacteria contribute to stress adaptation, dormancy, and persistence. AtaT, a type-II toxin in enterohemorrhagic E. coli, reportedly acetylates the α-amino group of the aminoacyl-moiety of initiator Met-tRNAf(Met), thus inhibiting translation initiation. Here, we show that...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Yashiro, Yuka, Sakaguchi, Yuriko, Suzuki, Tsutomu, Tomita, Kozo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7595197/
https://ncbi.nlm.nih.gov/pubmed/33116145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19281-z
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