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Ketohexokinase-A acts as a nuclear protein kinase that mediates fructose-induced metastasis in breast cancer

Harmful effects of high fructose intake on health have been widely reported. Although fructose is known to promote cancer, little is known about the underlying mechanisms. Here, we found that fructose triggers breast cancer metastasis through the ketohexokinase-A signaling pathway. Molecular experim...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kim, Jiyoung, Kang, Jengmin, Kang, Ye-Lim, Woo, Jongmin, Kim, Youngsoo, Huh, June, Park, Jong-Wan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7595112/
https://ncbi.nlm.nih.gov/pubmed/33116123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19263-1
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