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FIH permits NAA10 to catalyze the oxygen-dependent lysyl-acetylation of HIF-1α

The N-terminal acetyltransferase A (NatA) complex, which is composed of NAA10 and NAA15, catalyzes N-terminal acetylation of many proteins in a co-translational manner. Structurally, the catalytic subunit NAA10 was believed to have no activity toward an internal lysine residue because the gate of it...

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Publicat a:Redox Biol
Autors principals: Kang, Jengmin, Chun, Yang-Sook, Huh, June, Park, Jong-Wan
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142190/
https://ncbi.nlm.nih.gov/pubmed/30237125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.09.002
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