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Integrative transcriptome and chromatin landscape analysis reveals distinct epigenetic regulations in human memory B cells
Memory B cells (MBCs) are long-lived and produce high-affinity, generally, class-switched antibodies. Here, we use a multiparameter approach involving CD27 to segregate naïve B cells (NBC), IgD(+) unswitched (unsw)MBCs and IgG(+) or IgA(+) class-switched (sw)MBCs from humans of different age, sex an...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7595102/ https://ncbi.nlm.nih.gov/pubmed/33116135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19242-6 |
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