Multidirectional in vitro and in cellulo studies as a tool for identification of multi-target-directed ligands aiming at symptoms and causes of Alzheimer’s disease

Effective therapy of Alzheimer’s disease (AD) requires treatment with a combination of drugs that modulate various pathomechanisms contributing to the disease. In our research, we have focused on the development of multi-target-directed ligands – 5-HT(6) receptor antagonists and cholinesterase inhib...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Szałaj, Natalia, Godyń, Justyna, Jończyk, Jakub, Pasieka, Anna, Panek, Dawid, Wichur, Tomasz, Więckowski, Krzysztof, Zaręba, Paula, Bajda, Marek, Pislar, Anja, Malawska, Barbara, Sabate, Raimon, Więckowska, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594877/
https://ncbi.nlm.nih.gov/pubmed/33092411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1835882
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