Activation of carbonic anhydrases from human brain by amino alcohol oxime ethers: towards human carbonic anhydrase VII selective activators

The synthesis and carbonic anhydrase (CA; EC 4.2.1.1) activating effects of a series of oxime ether-based amino alcohols towards four human (h) CA isoforms expressed in human brain, hCA I, II, IV and VII, are described. Most investigated amino alcohol derivatives induced a consistent activation of t...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Nocentini, Alessio, Cuffaro, Doretta, Ciccone, Lidia, Orlandini, Elisabetta, Nencetti, Susanna, Nuti, Elisa, Rossello, Armando, Supuran, Claudiu T.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594847/
https://ncbi.nlm.nih.gov/pubmed/33103482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1838501
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