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Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics
BACKGROUND: Glioblastoma (GBM) consists of devastating neoplasms with high invasive capacity, which have been difficult to study in vitro in a human-derived model system. Therapeutic progress is also limited by cellular heterogeneity within and between tumors, among other factors such as therapy res...
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| Опубликовано в: : | Neuro Oncol |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7594554/ https://ncbi.nlm.nih.gov/pubmed/32297954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa091 |
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