Diagnostic biomarkers to differentiate sepsis from cytokine release syndrome in critically ill children

Chimeric antigen receptor (CAR) T-cells directed against CD19 have drastically altered outcomes for children with relapsed and refractory acute lymphoblastic leukemia (r/r ALL). Pediatric patients with r/r ALL treated with CAR-T are at increased risk of both cytokine release syndrome (CRS) and sepsi...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Diorio, Caroline, Shaw, Pamela A., Pequignot, Edward, Orlenko, Alena, Chen, Fang, Aplenc, Richard, Barrett, David M., Bassiri, Hamid, Behrens, Edward, DiNofia, Amanda M., Gonzalez, Vanessa, Koterba, Natalka, Levine, Bruce L., Maude, Shannon L., Meyer, Nuala J., Moore, Jason H., Paessler, Michele, Porter, David L., Bush, Jenny L., Siegel, Don L., Davis, Megan M., Zhang, Donglan, June, Carl H., Grupp, Stephan A., Melenhorst, J. Joseph, Lacey, Simon F., Weiss, Scott L., Teachey, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Immunobiology and Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594400/
https://ncbi.nlm.nih.gov/pubmed/33095872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002592
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