Class II HLA mismatch improves outcomes following haploidentical transplantation with posttransplant cyclophosphamide

HLA disparity is the major predictor of outcome following unrelated donor (UD) transplantation, where a single mismatch (mm) at the HLA-A, HLA-B, HLA-C, or HLA-DRB1 locus leads to increased mortality, and mismatching at multiple loci compounds this effect. In contrast, HLA disparity has not been sho...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Solomon, Scott R., Aubrey, Michael T., Zhang, Xu, Jackson, Katelin C., Morris, Lawrence E., Holland, H. Kent, Solh, Melhem M., Bashey, Asad
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594387/
https://ncbi.nlm.nih.gov/pubmed/33108457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003110
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