Prospective phase 2 trial of ixazomib after nonmyeloablative haploidentical peripheral blood stem cell transplant

Proteasome inhibition results in extensive immunomodulatory effects that augment natural killer cell cytotoxicity and inhibit aspects of T-cell, B-cell, and dendritic cell function. We performed a phase 2 study that examined the effects of ixazomib for graft-versus-host disease (GVHD) prophylaxis (u...

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Bibliographic Details
Published in:Blood Adv
Main Authors: Solomon, Scott R., Solh, Melhem, Zhang, Xu, Brown, Stacey, Jackson, Katelin C., Holland, H. Kent, Morris, Lawrence E., Bashey, Asad
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2020
Subjects:
Clinical Trials and Observations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422122/
https://ncbi.nlm.nih.gov/pubmed/32777064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001958
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