Prevention of SARS-CoV-2 cell entry: insight from in silico interaction of drug-like alkaloids with spike glycoprotein, human ACE2, and TMPRSS2

COVID-19 is a respiratory disease caused by SARS-CoV-2, an enveloped positive sense RNA virus. The SARS-CoV-2 spike glycoprotein, human angiotensin-converting enzyme 2 (ACE2) and human transmembrane protease serine 2 (TMPRSS2) are essential for the host cell-mediated viral entry. Targeting these pro...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Biomol Struct Dyn
Auteurs principaux: Gyebi, Gideon A., Adegunloye, Adegbenro P., Ibrahim, Ibrahim M., Ogunyemi, Oludare M., Afolabi, Saheed O., Ogunro, Olalekan B.
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594191/
https://ncbi.nlm.nih.gov/pubmed/33089728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2020.1835726
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