Accumulation of 8-hydroxydeoxyguanosine, L-arginine and Glucose Metabolites by Liver Tumor Cells Are the Important Characteristic Features of Metabolic Syndrome and Non-Alcoholic Steatohepatitis-Associated Hepatocarcinogenesis

To uncover mechanisms and explore novel biomarkers of obesity, type 2 diabetes (T2DM) and nonalcoholic steatohepatitis (NASH)-associated hepatocarcinogenesis, cellular and molecular alterations in the liver, and hepatocellular carcinomas (HCCs) were investigated in NASH model 60-week-old Tsumura, Su...

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Pubblicato in:Int J Mol Sci
Autori principali: Kakehashi, Anna, Suzuki, Shugo, Ishii, Naomi, Okuno, Takahiro, Kuwae, Yuko, Fujioka, Masaki, Gi, Min, Stefanov, Vasily, Wanibuchi, Hideki
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594076/
https://ncbi.nlm.nih.gov/pubmed/33092030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207746
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