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mTOR Activation in Liver Tumors Is Associated with Metabolic Syndrome and Non-Alcoholic Steatohepatitis in Both Mouse Models and Humans

Non-alcoholic steatohepatitis (NASH) can cause liver fibrosis and cirrhosis, with final progression to hepatocellular carcinoma (HCC) in some cases. Various factors have been suggested to be involved in the development of NASH. Considering the many possible contributing factors, we postulated that m...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Okuno, Takahiro, Kakehashi, Anna, Ishii, Naomi, Fujioka, Masaki, Gi, Min, Wanibuchi, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315895/
https://ncbi.nlm.nih.gov/pubmed/30469530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10120465
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