Synthesis of a New Class of Spirooxindole–Benzo[b]Thiophene-Based Molecules as Acetylcholinesterase Inhibitors

A series of new oxindole-based spiro-heterocycles bearing the benzo[b]thiophene motif were synthesized via a 1,3-dipolar cycloaddition reaction and their acetylcholinesterase (AChE) inhibitory activity was evaluated. All the synthesized compounds exhibited moderate inhibitory activities against AChE...

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Publicado en:Molecules
Main Authors: Barakat, Assem, Alshahrani, Saeed, Al-Majid, Abdullah Mohammed, Ali, M., Altowyan, Mezna Saleh, Islam, Mohammad Shahidul, Alamary, Abdullah Saleh, Ashraf, Sajda, Ul-Haq, Zaheer
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594047/
https://ncbi.nlm.nih.gov/pubmed/33066293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25204671
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