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Oxidative Stress and Alterations in the Antioxidative Defense System in Neuronal Cells Derived from NPC1 Patient-Specific Induced Pluripotent Stem Cells

Oxidative stress (OS) represents a state of an imbalanced amount of reactive oxygen species (ROS) and/or a hampered efficacy of the antioxidative defense system. Cells of the central nervous system are particularly sensitive to OS, as they have a massive need of oxygen to maintain proper function. C...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Jürs, Alexandra V., Völkner, Christin, Liedtke, Maik, Huth, Katharina, Lukas, Jan, Hermann, Andreas, Frech, Moritz J.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7593914/
https://ncbi.nlm.nih.gov/pubmed/33081384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207667
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