Structure of a Hallucinogen-Activated Gq-Coupled 5-HT(2A) Serotonin Receptor

Hallucinogens like lysergic acid diethylamide (LSD), psilocybin, and substituted N-benzyl phenylalkylamines are widely used recreationally with psilocybin being considered as a therapeutic for many neuropsychiatric disorders including depression, anxiety, and substance abuse. How psychedelics mediat...

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Pubblicato in:Cell
Autori principali: Kim, Kuglae, Che, Tao, Panova, Ouliana, DiBerto, Jeffrey F., Lyu, Jiankun, Krumm, Brian E., Wacker, Daniel, Robertson, Michael J., Seven, Alpay B., Nichols, David E., Shoichet, Brian K., Skiniotis, Georgios, Roth, Bryan L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7593816/
https://ncbi.nlm.nih.gov/pubmed/32946782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.08.024
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