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Amino Acid Starvation Sensitizes Resistant Breast Cancer to Doxorubicin-Induced Cell Death

Many clinical trials are beginning to assess the effectiveness of compounds known to regulate autophagy in patients receiving anti-cancer chemotherapy. However, autophagy inhibition, through exogenous inhibitors, or activation, through starvation, has revealed conflicting roles in cancer management...

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Publicat a:Front Cell Dev Biol
Autors principals: Thomas, Mark, Davis, Tanja, Nell, Theo, Sishi, Balindiwe, Engelbrecht, Anna-Mart
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7593593/
https://ncbi.nlm.nih.gov/pubmed/33178685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.565915
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