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Mechanisms of doxorubicin-induced drug resistance and drug resistant tumour growth in a murine breast tumour model

BACKGROUND: Doxorubicin is currently the most effective chemotherapeutic drug used to treat breast cancer. It has, however, been shown that doxorubicin can induce drug resistance resulting in poor patient prognosis and survival. Studies reported that the interaction between signalling pathways can p...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Christowitz, Claudia, Davis, Tanja, Isaacs, Ashwin, van Niekerk, Gustav, Hattingh, Suzel, Engelbrecht, Anna-Mart
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670209/
https://ncbi.nlm.nih.gov/pubmed/31370818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5939-z
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